diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
index 2a5106c5f2..178df30cf3 100644
--- a/.github/workflows/main.yml
+++ b/.github/workflows/main.yml
@@ -251,8 +251,8 @@ jobs:
       NODE_VERSION: 22
       # Note that the versions below are updated by `update_pyodide_versions()` in our weekly cronjob.
       # The versions of pyodide-build and the Pyodide runtime may differ.
-      PYODIDE_VERSION: 0.29.0
-      PYODIDE_BUILD_VERSION: 0.30.9
+      PYODIDE_VERSION: 0.29.1
+      PYODIDE_BUILD_VERSION: 0.31.1
       PYTHON_VERSION: 3.13.2
     steps:
     - uses: actions/checkout@v3
diff --git a/hypothesis-python/tox.ini b/hypothesis-python/tox.ini
index bbb6027310..8066e7f401 100644
--- a/hypothesis-python/tox.ini
+++ b/hypothesis-python/tox.ini
@@ -191,9 +191,9 @@ setenv=
 deps=
     -r../requirements/test.txt
     django42: django==4.2.27
-    django52: django==5.2.9
-    django60: django==6.0.0
-    django-nocontrib: django==6.0.0
+    django52: django==5.2.10
+    django60: django==6.0.1
+    django-nocontrib: django==6.0.1
 commands =
     python -bb -X dev -m tests.django.manage test tests.django {posargs}
 
diff --git a/requirements/coverage.txt b/requirements/coverage.txt
index e2c3f8890b..ec7403efd6 100644
--- a/requirements/coverage.txt
+++ b/requirements/coverage.txt
@@ -44,7 +44,7 @@ packaging==25.0
     #   pytest
 pandas==2.3.3
     # via -r requirements/coverage.in
-pathspec==0.12.1
+pathspec==1.0.3
     # via black
 pexpect==4.9.0
     # via -r requirements/test.in
diff --git a/requirements/crosshair.txt b/requirements/crosshair.txt
index 868a73fa65..af5f5cbf56 100644
--- a/requirements/crosshair.txt
+++ b/requirements/crosshair.txt
@@ -25,7 +25,7 @@ exceptiongroup==1.3.1 ; python_version < "3.11"
     #   pytest
 execnet==2.1.2
     # via pytest-xdist
-hypothesis==6.148.11
+hypothesis==6.150.0
     # via hypothesis-crosshair
 hypothesis-crosshair==0.0.27
     # via -r requirements/crosshair.in
diff --git a/requirements/fuzzing.txt b/requirements/fuzzing.txt
index 7a6c195324..7d9a28a61c 100644
--- a/requirements/fuzzing.txt
+++ b/requirements/fuzzing.txt
@@ -6,7 +6,7 @@
 #
 annotated-types==0.7.0
     # via -r requirements/coverage.in
-anyio==4.12.0
+anyio==4.12.1
     # via starlette
 async-timeout==5.0.1
     # via redis
@@ -57,7 +57,7 @@ hyperframe==6.1.0
     # via h2
 hypofuzz==25.11.1
     # via -r requirements/fuzzing.in
-hypothesis[cli,watchdog]==6.148.11
+hypothesis[cli,watchdog]==6.150.0
     # via hypofuzz
 idna==3.11
     # via
@@ -89,7 +89,7 @@ packaging==25.0
     #   pytest
 pandas==2.3.3
     # via -r requirements/coverage.in
-pathspec==0.12.1
+pathspec==1.0.3
     # via black
 pexpect==4.9.0
     # via -r requirements/test.in
@@ -147,7 +147,7 @@ sortedcontainers==2.4.0
     #   hypothesis
     #   hypothesis (hypothesis-python/pyproject.toml)
     #   trio
-starlette==0.50.0
+starlette==0.51.0
     # via hypofuzz
 taskgroup==0.2.2
     # via hypercorn
diff --git a/requirements/tools.txt b/requirements/tools.txt
index c673c3be62..f50e1af140 100644
--- a/requirements/tools.txt
+++ b/requirements/tools.txt
@@ -8,7 +8,7 @@ accessible-pygments==0.0.5
     # via furo
 alabaster==1.0.0
     # via sphinx
-anyio==4.12.0
+anyio==4.12.1
     # via
     #   starlette
     #   watchfiles
@@ -32,13 +32,13 @@ black==25.12.0
     # via shed
 blinker==1.9.0
     # via pelican
-build==1.3.0
+build==1.4.0
     # via
     #   -r requirements/tools.in
     #   pip-tools
 cachetools==6.2.4
     # via tox
-certifi==2025.11.12
+certifi==2026.1.4
     # via requests
 cffi==2.0.0
     # via cryptography
@@ -70,7 +70,7 @@ decorator==5.2.1
     # via ipython
 distlib==0.4.0
     # via virtualenv
-django==5.2.9
+django==5.2.10
     # via -r requirements/tools.in
 docutils==0.21.2
     # via
@@ -93,7 +93,7 @@ executing==2.2.1
     # via stack-data
 feedgenerator==2.2.1
     # via pelican
-filelock==3.20.2
+filelock==3.20.3
     # via
     #   tox
     #   virtualenv
@@ -113,7 +113,7 @@ importlib-metadata==8.7.1
     # via keyring
 iniconfig==2.3.0
     # via pytest
-ipython==8.37.0
+ipython==8.38.0
     # via -r requirements/tools.in
 isort==7.0.0
     # via shed
@@ -184,7 +184,7 @@ packaging==25.0
     #   twine
 parso==0.8.5
     # via jedi
-pathspec==0.12.1
+pathspec==1.0.3
     # via
     #   black
     #   mypy
@@ -231,7 +231,7 @@ pyproject-hooks==1.2.0
     # via
     #   build
     #   pip-tools
-pyright==1.1.407
+pyright==1.1.408
     # via -r requirements/tools.in
 pytest==9.0.2
     # via
@@ -271,7 +271,7 @@ rich==14.2.0
     # via
     #   pelican
     #   twine
-ruff==0.14.10
+ruff==0.14.11
     # via -r requirements/tools.in
 secretstorage==3.5.0
     # via keyring
@@ -322,7 +322,7 @@ sqlparse==0.5.5
     # via django
 stack-data==0.6.3
     # via ipython
-starlette==0.50.0
+starlette==0.51.0
     # via sphinx-autobuild
 tokenize-rt==6.2.0
     # via pyupgrade
@@ -337,7 +337,7 @@ tomli==2.3.0
     #   pytest
     #   sphinx
     #   tox
-tox==4.33.0
+tox==4.34.1
     # via -r requirements/tools.in
 traitlets==5.14.3
     # via
@@ -376,13 +376,13 @@ typing-extensions==4.15.0
     #   virtualenv
 unidecode==1.4.0
     # via pelican
-urllib3==2.6.2
+urllib3==2.6.3
     # via
     #   requests
     #   twine
 uvicorn==0.40.0
     # via sphinx-autobuild
-virtualenv==20.35.4
+virtualenv==20.36.1
     # via tox
 watchdog==6.0.0
     # via -r requirements/tools.in
@@ -392,7 +392,7 @@ watchfiles==1.1.1
     #   sphinx-autobuild
 wcwidth==0.2.14
     # via prompt-toolkit
-websockets==15.0.1
+websockets==16.0
     # via sphinx-autobuild
 wheel==0.45.1
     # via pip-tools
diff --git a/tooling/src/hypothesistooling/__main__.py b/tooling/src/hypothesistooling/__main__.py
index 595ea6d001..47fbc324bc 100644
--- a/tooling/src/hypothesistooling/__main__.py
+++ b/tooling/src/hypothesistooling/__main__.py
@@ -390,8 +390,8 @@ def update_python_versions():
 
 DJANGO_VERSIONS = {
     "4.2": "4.2.27",
-    "5.2": "5.2.9",
-    "6.0": "6.0.0",
+    "5.2": "5.2.10",
+    "6.0": "6.0.1",
 }