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Boltz contains an insecure deserialization vulnerability in its molecule loading functionality

High severity GitHub Reviewed Published Feb 3, 2026 to the GitHub Advisory Database • Updated Feb 4, 2026

Package

pip boltz (pip)

Affected versions

<= 2.0.0

Patched versions

None

Description

Boltz 2.0.0 contains an insecure deserialization vulnerability in its molecule loading functionality. The application uses Python pickle to deserialize molecule data files without validation. An attacker with the ability to place a malicious pickle file in a directory processed by boltz can achieve arbitrary code execution when the file is loaded.

References

Published by the National Vulnerability Database Feb 3, 2026
Published to the GitHub Advisory Database Feb 3, 2026
Reviewed Feb 4, 2026
Last updated Feb 4, 2026

Severity

High

CVSS overall score

This score calculates overall vulnerability severity from 0 to 10 and is based on the Common Vulnerability Scoring System (CVSS).
/ 10

CVSS v3 base metrics

Attack vector
Local
Attack complexity
Low
Privileges required
None
User interaction
None
Scope
Unchanged
Confidentiality
High
Integrity
High
Availability
High

CVSS v3 base metrics

Attack vector: More severe the more the remote (logically and physically) an attacker can be in order to exploit the vulnerability.
Attack complexity: More severe for the least complex attacks.
Privileges required: More severe if no privileges are required.
User interaction: More severe when no user interaction is required.
Scope: More severe when a scope change occurs, e.g. one vulnerable component impacts resources in components beyond its security scope.
Confidentiality: More severe when loss of data confidentiality is highest, measuring the level of data access available to an unauthorized user.
Integrity: More severe when loss of data integrity is the highest, measuring the consequence of data modification possible by an unauthorized user.
Availability: More severe when the loss of impacted component availability is highest.
CVSS:3.1/AV:L/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H

EPSS score

Exploit Prediction Scoring System (EPSS)

This score estimates the probability of this vulnerability being exploited within the next 30 days. Data provided by FIRST.
(18th percentile)

Weaknesses

Deserialization of Untrusted Data

The product deserializes untrusted data without sufficiently ensuring that the resulting data will be valid. Learn more on MITRE.

CVE ID

CVE-2025-70560

GHSA ID

GHSA-fjm6-8xp2-4fwc

Source code

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